In some embodiments, the formulation or composition has a retention time in the ear of at least 5 minutes, at least 15 minutes, at least 30 minutes, at least 1 hour, at least 4 hours, at least 6 hours, at least 12 hours, at least 18 hours, at least 1 day, at least 2 days, at least 3 days, at least 4 days, at least 5 days, at least 6 days, at least 7 days, at least 10 days, at least 12 days, at least 14 days, at leastl8 days, at least 21 days, at least 25 days, at least 30 days, at least 45 days, at least 2 months, at least 3 months, at least 4 months, at least 5 months, at least 6 months, at least 9 months or at least 1 year
Indian J Surg Oncol
One pharmacy might assign a 28-day beyond-use date while another assigns 90 days for what appears to be a similar formulation
A fast SHAKE algorithm to solve distance constraint equations for small molecules in molecular dynamics simulations
Jones BK, Monks BR, Liebhaber SA, Cooke NE
doi: 10.1080/15592324.2020.1722447 28 VadasseryJ.RanfS.DrzewieckiC.MithferA.MazarsC.ScheelD.et al
